Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome Running title: Sinisalo et al.; Predisposing haplotype to acute coronary syndrome
نویسندگان
چکیده
HUH Heart & Lung Center, Helsinki University Hospital; Haartman Institute, University of Helsinki; Wihuri Research Institute; National Institute for Health and Welfare; Institute for Molecular Medicine Finland (FIMM), Helsinki; Institute of Clinical Medicine, University of Oulu, Oulu; School of Medicine, University of Tampere; Heart Center, Tampere University Hospital, Tampere, Finland; Department of Medicine, Massachusetts General Hospital, Boston, MA; Cardiovascular Epidemiology & Genetics, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain
منابع مشابه
Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary Syndrome.
BACKGROUND The HLA-DRB1*01 allele of the human leukocyte antigen has been associated with acute coronary syndrome. Genome-wide association studies have revealed associations with human leukocyte antigen and non-human leukocyte antigen genes of 3 major histocompatibility complex gene classes but not at allelic level. METHODS AND RESULTS We conducted a large-scale genetic analysis on a case-con...
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تاریخ انتشار 2015